本課程主旨在於介紹基因與醫學在族群健康中的重要性，近年來隨著高通量基因體研究技術發展，不同層次的基因分子被廣泛研究，內容包含單核甘酸多型性、拷貝數、甲基化以及基因表現數值等等，均在個體及族群層次上被證明是重要的影響因子。近年來世界各國的大型人體資料庫也將基因數據做為重要的收集資料，因此在公共衛生的研究上基因已是不可或缺的一部分。本課程將由不同層次的基因分子生物意義介紹起始，期待透過這些內容讓學生對於分析各式基因數據前能理解這些分子在細胞與個體上的重要性，接著會透過研究實例與分析操作讓學生接觸實際實驗測量產生之數據，以期能讓學生體會真實研究進行之狀況。課程後段則將介紹目前在醫院上可使用的基因檢測相關工具，讓學生能夠感受基因資料在實務上的重要性，以期讓生物理論與實務應用可以緊密結合。

This course aims to introduce the importance of genetics and medicine in population health. Recently, with the advancements in high-throughput genetics technologies, different genetic molecules, including single nucleotide polymorphism (SNP), copy number variation (CNV), methylation and gene expression, have been intensively studied and reported as important factors affecting individual and population health. Furthermore, many counties have included genetic data into their large-scale biobanks and thus genetics has become an essential component in public health researches. In this course, we will first introduce the functions and mechanism of different genetic molecules in order to let students have better understanding of the biological roles of these molecules. Next, we will provide research examples and computer practices to let students become more familiar with real data. Lastly, we will introduce currently available genetic testing tools in the real world to let students understand what genetics can do nowadays.